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A nuclear F-actin scaffold stabilizes RNP droplets against gravity in large cells

The size of a typical eukaryotic cell is on the order of ≈10 μm. However, some cell types grow to very large sizes, including oocytes (immature eggs) of organisms from humans to starfish. For example, oocytes of the frog X. laevis grow to a diameter ≥1 mm. They contain a correspondingly large nucleu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feric, Marina, Brangwynne, Clifford P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789854/
https://ncbi.nlm.nih.gov/pubmed/23995731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2830
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