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F-actin scaffold stabilizes lamellar bodies during surfactant secretion

Alveolar type 2 (AT2) cells secrete surfactant that forms a protective layer on the lung's alveolar epithelium. Vesicles called lamellar bodies (LBs) store surfactant. Failure of surfactant secretion, which causes severe lung disease, relates to the manner in which LBs undergo exocytosis during...

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Autores principales: Islam, Mohammad N., Gusarova, Galina A., Monma, Eiji, Das, Shonit R., Bhattacharya, Jahar
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920216/
https://ncbi.nlm.nih.gov/pubmed/24213916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00252.2013
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