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F-actin scaffold stabilizes lamellar bodies during surfactant secretion
Alveolar type 2 (AT2) cells secrete surfactant that forms a protective layer on the lung's alveolar epithelium. Vesicles called lamellar bodies (LBs) store surfactant. Failure of surfactant secretion, which causes severe lung disease, relates to the manner in which LBs undergo exocytosis during...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920216/ https://ncbi.nlm.nih.gov/pubmed/24213916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00252.2013 |
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