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F-actin scaffold stabilizes lamellar bodies during surfactant secretion

Alveolar type 2 (AT2) cells secrete surfactant that forms a protective layer on the lung's alveolar epithelium. Vesicles called lamellar bodies (LBs) store surfactant. Failure of surfactant secretion, which causes severe lung disease, relates to the manner in which LBs undergo exocytosis during...

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Bibliographische Detailangaben
Hauptverfasser: Islam, Mohammad N., Gusarova, Galina A., Monma, Eiji, Das, Shonit R., Bhattacharya, Jahar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920216/
https://ncbi.nlm.nih.gov/pubmed/24213916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00252.2013
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