F-actin scaffold stabilizes lamellar bodies during surfactant secretion

Alveolar type 2 (AT2) cells secrete surfactant that forms a protective layer on the lung's alveolar epithelium. Vesicles called lamellar bodies (LBs) store surfactant. Failure of surfactant secretion, which causes severe lung disease, relates to the manner in which LBs undergo exocytosis during...

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Bibliographic Details
Main Authors: Islam, Mohammad N., Gusarova, Galina A., Monma, Eiji, Das, Shonit R., Bhattacharya, Jahar
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920216/
https://ncbi.nlm.nih.gov/pubmed/24213916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00252.2013
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