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Endothelial mitochondria determine rapid barrier failure in chemical lung injury

Acid aspiration, which can result from several etiologies, including postoperative complications, leads to direct contact of concentrated hydrochloric acid (HCl) with the alveolar epithelium. As a result, rapid endothelial activation induces alveolar inflammation, leading to life-threatening pulmona...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Hough, Rebecca F., Islam, Mohammad N., Gusarova, Galina A., Jin, Guangchun, Das, Shonit, Bhattacharya, Jahar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413830/
https://ncbi.nlm.nih.gov/pubmed/30728333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124329
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