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Actin fence therapy with exogenous V12Rac1 protects against acute lung injury
High mortality in acute lung injury (ALI) results from sustained proinflammatory signaling by alveolar receptors, such as TNF-α receptor type 1 (TNFR1). Factors that determine the sustained signaling are not known. Unexpectedly, optical imaging of live alveoli revealed a major TNF-α–induced surge of...
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| Vydáno v: | JCI Insight |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026177/ https://ncbi.nlm.nih.gov/pubmed/33749665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135753 |
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