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Wessim: a whole-exome sequencing simulator based on in silico exome capture

Summary: We propose a targeted re-sequencing simulator Wessim that generates synthetic exome sequencing reads from a given sample genome. Wessim emulates conventional exome capture technologies, including Agilent’s SureSelect and NimbleGen’s SeqCap, to generate DNA fragments from genomic target regi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Sangwoo, Jeong, Kyowon, Bafna, Vineet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624799/
https://ncbi.nlm.nih.gov/pubmed/23413434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt074
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