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Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing
SUMMARY: Tumour evolution results in progressive cancer phenotypes such as metastatic spread and treatment resistance. To better treat cancers, we must characterize tumour evolution and the genetic events that confer progressive phenotypes. This is facilitated by high coverage genome or exome sequen...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6691334/ https://ncbi.nlm.nih.gov/pubmed/30615054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty1063 |
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