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Simulating the dynamics of targeted capture sequencing with CapSim

MOTIVATION: Targeted sequencing using capture probes has become increasingly popular in clinical applications due to its scalability and cost-effectiveness. The approach also allows for higher sequencing coverage of the targeted regions resulting in better analysis statistical power. However, becaus...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Cao, Minh Duc, Ganesamoorthy, Devika, Zhou, Chenxi, Coin, Lachlan J M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192212/
https://ncbi.nlm.nih.gov/pubmed/29092025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx691
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