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SimRVSequences: an R package to simulate genetic sequence data for pedigrees

SUMMARY: We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample o...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Nieuwoudt, Christina, Brooks-Wilson, Angela, Graham, Jinko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141864/
https://ncbi.nlm.nih.gov/pubmed/31764964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz881
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