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Simulating pedigrees ascertained for multiple disease-affected relatives

BACKGROUND: Studies that ascertain families containing multiple relatives affected by disease can be useful for identification of causal, rare variants from next-generation sequencing data. RESULTS: We present the R package SimRVPedigree, which allows researchers to simulate pedigrees ascertained on...

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Bibliografiset tiedot
Julkaisussa:Source Code Biol Med
Päätekijät: Nieuwoudt, Christina, Jones, Samantha J., Brooks-Wilson, Angela, Graham, Jinko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190569/
https://ncbi.nlm.nih.gov/pubmed/30356812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13029-018-0069-6
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