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Interferon-γ-Induced Necrosis: An Antitumor Biotherapeutic Perspective

Interferon (IFN)-γ—like the well-known antitumor biotherapeutic IFN-α—is a powerful antiproliferative and immune modulatory cytokine, but mixed results from clinical trials, together with issues of systemic toxicity, have dampened enthusiasm for its use in the treatment of cancer. We suggest that at...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Balachandran, Siddharth, Adams, Gregory P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624769/
https://ncbi.nlm.nih.gov/pubmed/23570383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0087
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