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Development of interferon γ-based immunocytokines targeting renal cancer

Advanced renal cancer is an incurable malignancy in need of novel therapeutic avenues. We have generated interferon γ (IFNγ)-based fusion antibodies (immunocytokines) that target CD70, a putative biomarker of renal cancer. These immunocytokines efficiently labeled renal cancer cells, and, when combi...

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Détails bibliographiques
Auteurs principaux: Chen, Peirong, Balachandran, Siddharth
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782162/
https://ncbi.nlm.nih.gov/pubmed/24073376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24964
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