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Interferon-γ-Induced Necrosis: An Antitumor Biotherapeutic Perspective

Interferon (IFN)-γ—like the well-known antitumor biotherapeutic IFN-α—is a powerful antiproliferative and immune modulatory cytokine, but mixed results from clinical trials, together with issues of systemic toxicity, have dampened enthusiasm for its use in the treatment of cancer. We suggest that at...

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Detalhes bibliográficos
Main Authors: Balachandran, Siddharth, Adams, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624769/
https://ncbi.nlm.nih.gov/pubmed/23570383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0087
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