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The PKCθ pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells

Fra-1 is aberrantly expressed in a large number of cancer cells and tissues, and emerging evidence suggests an important role for this Fos family protein in both oncogenesis and the progression or maintenance of many tumour types. Here, we show that the concentration of Fra-1 is high in invasive oes...

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Main Authors: Belguise, Karine, Milord, Sandrine, Galtier, Florence, Moquet-Torcy, Gabriel, Piechaczyk, Marc, Chalbos, Dany
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624663/
https://ncbi.nlm.nih.gov/pubmed/22286759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.659
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