Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2

Aberrant constitutive expression of c-Rel, p65 and p50 NF-κB subunits has been reported in over 90% of breast cancers1,2. Recently, we characterized a de novo RelB NF-κB subunit synthesis pathway, induced by the cytomegalovirus (CMV) IE1 protein, in which binding of p50/p65 NF-κB and c-Jun/Fra-2 AP-...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xiaobo, Belguise, Karine, Kersual, Nathalie, Kirsch, Kathrin H., Mineva, Nora D., Galtier, Florence, Chalbos, Dany, Sonenshein, Gail E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Macmillan Magazines Ltd. 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394707/
https://ncbi.nlm.nih.gov/pubmed/17369819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1559
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