Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser(2), Ser(5), and Ser(7) within the Carboxyl-terminal Domain Repeat

The human transcription elongation regulator TCERG1 physically couples transcription elongation and splicing events by interacting with splicing factors through its N-terminal WW domains and the hyperphosphorylated C-terminal domain (CTD) of RNA polymerase II through its C-terminal FF domains. Here,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Jiangxin, Fan, Shilong, Lee, Chul-Jin, Greenleaf, Arno L., Zhou, Pei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624469/
https://ncbi.nlm.nih.gov/pubmed/23436654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460238
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