Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

The release of humoral factors between cancer cells and the microenvironmental cells is critical for metastasis; however, the roles of secreted miRNAs in non-cell autonomous cancer progression against microenvironmental cells remain largely unknown. Here, we demonstrate that the neutral sphyngomyeli...

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Hlavní autoři: Kosaka, Nobuyoshi, Iguchi, Haruhisa, Hagiwara, Keitaro, Yoshioka, Yusuke, Takeshita, Fumitaka, Ochiya, Takahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624465/
https://ncbi.nlm.nih.gov/pubmed/23439645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.446831
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