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Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

The existence of circulating microRNAs (miRNAs) in the blood of cancer patients has raised the possibility that miRNAs may serve as a novel diagnostic marker. However, the secretory mechanism and biological function of extracellular miRNAs remain unclear. Here, we show that miRNAs are released throu...

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Detalhes bibliográficos
Main Authors: Kosaka, Nobuyoshi, Iguchi, Haruhisa, Yoshioka, Yusuke, Takeshita, Fumitaka, Matsuki, Yasushi, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878508/
https://ncbi.nlm.nih.gov/pubmed/20353945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107821
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