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Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

The existence of circulating microRNAs (miRNAs) in the blood of cancer patients has raised the possibility that miRNAs may serve as a novel diagnostic marker. However, the secretory mechanism and biological function of extracellular miRNAs remain unclear. Here, we show that miRNAs are released throu...

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Hlavní autoři: Kosaka, Nobuyoshi, Iguchi, Haruhisa, Yoshioka, Yusuke, Takeshita, Fumitaka, Matsuki, Yasushi, Ochiya, Takahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878508/
https://ncbi.nlm.nih.gov/pubmed/20353945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107821
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