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p19(ARF) and Ras(V12) Offer Opposing Regulation of DHX33 Translation To Dictate Tumor Cell Fate

DHX33 is a pivotal DEAH-box RNA helicase in the multistep process of RNA polymerase I-directed transcription of the ribosomal DNA locus. We explored the regulation of DHX33 expression by Ras(V12) and ARF to determine DHX33's role in sensing these opposing signals to regulate ribosome biogenesis...

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Detalhes bibliográficos
Main Authors: Zhang, Yandong, Saporita, Anthony J., Weber, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624250/
https://ncbi.nlm.nih.gov/pubmed/23401854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01220-12
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