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Identification of DHX33 as a Mediator of rRNA Synthesis and Cell Growth

In this report, we employed a lentiviral RNA interference screen to discover nucleolar DEAD/DEAH-box helicases involved in RNA polymerase I (Pol I)-mediated transcriptional activity. Our screen identified DHX33 as an important modulator of 47S rRNA transcription. We show that DHX33 is a cell cycle-r...

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Autors principals: Zhang, Yandong, Forys, Jason T., Miceli, Alexander P., Gwinn, Abigail S., Weber, Jason D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232920/
https://ncbi.nlm.nih.gov/pubmed/21930779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05832-11
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