Targeting IκB Proteins for HIV Latency Activation: the Role of Individual IκB and NF-κB Proteins

Latently infected cell reservoirs represent the main barrier to HIV eradication. Combination antiretroviral therapy (cART) effectively blocks viral replication but cannot purge latent provirus. One approach to HIV eradication could include cART to block new infections plus an agent to activate laten...

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Main Authors: Fernandez, Guerau, Zaikos, Thomas D., Khan, Sohrab Z., Jacobi, Ashley M., Behlke, Mark A., Zeichner, Steven L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624191/
https://ncbi.nlm.nih.gov/pubmed/23365428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03251-12
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