Nuclear Transit and HIV LTR Binding of NF-κB Subunits Held by IκB Proteins: Implications for HIV-1 Activation

No effective therapy to eliminate the HIV latently infected cell reservoir has been developed. One approach, “shock and kill”, employs agents that activate HIV, subsequently killing the activated infected cells and/or virus. Shock and kill requires agents that safely and effectively activate HIV. On...

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Bibliographic Details
Published in:Viruses
Main Authors: Khan, Sohrab Z., Gasperino, Sofia, Zeichner, Steven L.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949894/
https://ncbi.nlm.nih.gov/pubmed/31888181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11121162
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