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Poly(beta-amino ester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo

Small cell lung cancer (SCLC) is an aggressive disease with one of the highest case-fatality rates among cancer. The recommended therapy for SCLC has not changed significantly over the past 30 years; new therapeutic approaches are a critical need. TP53 is mutated in the majority of SCLC cases and it...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kamat, Chandrashekhar D., Shmueli, Ron B., Connis, Nick, Rudin, Charles M., Green, Jordan J., Hann, Christine L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624031/
https://ncbi.nlm.nih.gov/pubmed/23364678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0956
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