HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial

BACKGROUND: Human papilloma virus type 16 (HPV16)-induced gynecological cancers, in particular cervical cancers, are found in many women worldwide. The HPV16 encoded oncoproteins E6 and E7 are tumor-specific targets for the adaptive immune system permitting the development of an HPV16-synthetic long...

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Main Authors: van Poelgeest, Mariette I E, Welters, Marij J P, van Esch, Edith M G, Stynenbosch, Linda F M, Kerpershoek, Gijs, van Persijn van Meerten, Els L, van den Hende, Muriel, Löwik, Margriet J G, Berends-van der Meer, Dorien M A, Fathers, Lorraine M, Valentijn, A Rob P M, Oostendorp, Jaap, Fleuren, Gert Jan, Melief, Cornelis J M, Kenter, Gemma G, van der Burg, Sjoerd H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623745/
https://ncbi.nlm.nih.gov/pubmed/23557172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-88
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