Pre-existing inflammatory immune microenvironment predicts the clinical response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 vaccination

BACKGROUND: Vulvar high-grade squamous intraepithelial lesion (vHSIL) is predominantly induced by high-risk human papilloma virus type 16 (HPV16). In two independent trials, therapeutic vaccination against the HPV16 E6 and E7 oncoproteins resulted in objective partial and complete responses (PRs/CRs...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Abdulrahman, Ziena, de Miranda, Noel, van Esch, Edith M G, de Vos van Steenwijk, Peggy J, Nijman, Hans W, J. P. Welters, Marij, van Poelgeest, Mariette I E, van der Burg, Sjoerd H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Immunotherapy Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069269/
https://ncbi.nlm.nih.gov/pubmed/32169871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000563
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados