Cell mediated immunity against HPV16 E2, E6 and E7 peptides in women with incident CIN and in constantly HPV-negative women followed-up for 10-years

BACKGROUND: Virus-specific cell-mediated immunity (CMI) plays a role in the outcome of genital HPV infections. To cast further light on the question why most women clear their HPV infection while others develop high-grade cervical intraepithelial neoplasia (CIN), we analyzed HPV16 E2-, E6- and E7 -s...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Paaso, Anna, Koskimaa, Hanna-Mari, Welters, Marij JP, Grénman, Seija, Syrjänen, Kari, van der Burg, Sjoerd H, Syrjänen, Stina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448180/
https://ncbi.nlm.nih.gov/pubmed/25990808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0498-9
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