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A Physiologically Based Pharmacokinetic Model of Rifampin in Mice

One problem associated with regimen-based development of antituberculosis (anti-TB) drugs is the difficulty of a systematic and thorough in vivo evaluation of the large number of possible regimens that arise from consideration of multiple drugs tested together. A mathematical model capable of simula...

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Bibliografiske detaljer
Main Authors: Lyons, Michael A., Reisfeld, Brad, Yang, Raymond S. H., Lenaerts, Anne J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623338/
https://ncbi.nlm.nih.gov/pubmed/23357766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01567-12
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