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Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model

One critical approach to preclinical evaluation of anti-tuberculosis (anti-TB) drugs is the study of correlations between drug exposure and efficacy in animal TB infection models. While such pharmacokinetic/pharmacodynamic (PK/PD) studies are useful for the identification of optimal clinical dosing...

詳細記述

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書誌詳細
出版年:J Pharmacokinet Pharmacodyn
主要な著者: Lyons, Michael A., Lenaerts, Anne J.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506877/
https://ncbi.nlm.nih.gov/pubmed/26026426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9419-z
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