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Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model

One critical approach to preclinical evaluation of anti-tuberculosis (anti-TB) drugs is the study of correlations between drug exposure and efficacy in animal TB infection models. While such pharmacokinetic/pharmacodynamic (PK/PD) studies are useful for the identification of optimal clinical dosing...

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Detalhes bibliográficos
Publicado no:J Pharmacokinet Pharmacodyn
Main Authors: Lyons, Michael A., Lenaerts, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506877/
https://ncbi.nlm.nih.gov/pubmed/26026426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9419-z
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