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Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model
One critical approach to preclinical evaluation of anti-tuberculosis (anti-TB) drugs is the study of correlations between drug exposure and efficacy in animal TB infection models. While such pharmacokinetic/pharmacodynamic (PK/PD) studies are useful for the identification of optimal clinical dosing...
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| Veröffentlicht in: | J Pharmacokinet Pharmacodyn |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506877/ https://ncbi.nlm.nih.gov/pubmed/26026426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9419-z |
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