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The Phosphatase-Transcription Activator EYA1 Is Targeted by Anaphase-Promoting Complex/Cdh1 for Degradation at M-to-G(1) Transition

The phosphatase and transactivator EYA family proteins are overexpressed in many cancer cell lines and are abundantly distributed in undifferentiated cells during development. Loss-of-function studies have shown that EYA1 is required for cell proliferation and survival during mammalian organogenesis...

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Detalhes bibliográficos
Main Authors: Sun, Jianbo, Karoulia, Zoi, Wong, Elaine Y. M., Ahmed, Mohi, Itoh, Keiji, Xu, Pin-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623089/
https://ncbi.nlm.nih.gov/pubmed/23263983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01516-12
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