Laddar...

Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2

Inner ear hair cell differentiation requires Atoh1 function, while Eya1, Six1 and Sox2 are coexpressed in sensory progenitors and mutations in these genes cause sensorineural hearing loss. However, how these genes are linked functionally and the transcriptional networks controlling hair cell inducti...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ahmed, Mohi, Wong, Elaine Y-M., Sun, Jianbo, Xu, Jinshu, Wang, Feng, Xu, Pin-Xian
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285434/
https://ncbi.nlm.nih.gov/pubmed/22340499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.12.006
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!