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EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

Inner ear neurogenesis depends upon the function of the proneural basic helix-loop-helix (bHLH) transcription factors NEUROG1 and NEUROD1. However, the transcriptional regulation of these factors is unknown. Here, using loss- and gain-of-function models, we show that EYA1 and SIX1 are crucial otic n...

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Detalhes bibliográficos
Main Authors: Ahmed, Mohi, Xu, Jinshu, Xu, Pin-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347689/
https://ncbi.nlm.nih.gov/pubmed/22513373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071670
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