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The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms

BACKGROUND AND PURPOSE: The transient receptor potential vanilloid type 1 (TRPV1) plays a fundamental role in the detection of heat and inflammatory pain responses. Here we investigated the contribution of two potential endogenous ligands [9- and 13- hydroxyoctadecadienoic acid (HODE)] to TRPV1-medi...

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Detalhes bibliográficos
Main Authors: Alsalem, Mohammad, Wong, Amy, Millns, Paul, Arya, Pallavi Huma, Chan, Michael Siang Liang, Bennett, Andrew, Barrett, David A, Chapman, Victoria, Kendall, David A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623065/
https://ncbi.nlm.nih.gov/pubmed/23278358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12092
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