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TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats

TRPV3 is a nonselective cation channel activated by temperatures above 33°C and is reported to be localized in keratinocytes and nervous tissue. To investigate a role for TRPV3 in pain modulation, we conducted a series of in vivo electrophysiological studies on spinal and brain nociceptive neurons....

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: McGaraughty, Steve, Chu, Katharine L., Xu, Jun, Leys, Laura, Radek, Richard J., Dart, Michael J., Gomtsyan, Arthur, Schmidt, Robert G., Kym, Philip R., Brederson, Jill-Desiree
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539442/
https://ncbi.nlm.nih.gov/pubmed/28468993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00104.2017
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