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Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat

BACKGROUND: Olvanil (NE 19550) is a non-pungent synthetic analogue of capsaicin, the natural pungent ingredient of capsicum which activates the transient receptor potential vanilloid type-1 (TRPV1) channel and was developed as a potential analgesic compound. Olvanil has potent anti-hyperalgesic effe...

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Dades bibliogràfiques
Publicat a:BMC Pharmacol Toxicol
Autors principals: Alsalem, Mohammad, Millns, Paul, Altarifi, Ahmad, El-Salem, Khalid, Chapman, Victoria, Kendall, David A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955132/
https://ncbi.nlm.nih.gov/pubmed/27439609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0074-9
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