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Identification of molecular vulnerabilities in human multiple myeloma cells by RNAi lethality screening of the druggable genome
Despite recent advances in targeted treatments for multiple myeloma (MM), optimal molecular therapeutic targets have yet to be identified. To functionally identify critical molecular targets, we conducted a genome-scale lethality study in MM cells using small interfering RNAs (siRNA). We validated t...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622723/ https://ncbi.nlm.nih.gov/pubmed/22147262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2781 |
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