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Thiol Modification By Pharmacologically Active Agents of the Diazeniumdiolate Class

Promising drug candidates of the diazeniumdiolate (NONOate) chemical family include several types of thiol modification among their mechanisms of action: 1) drugs designed to release nitric oxide (NO) on reaction with the thiol group of glutathione (GSH) arylate the GSH, a step that removes reducing...

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Autores principales: Maciag, Anna E., Holland, Ryan J., Saavedra, Joseph E., Chakrapani, Harinath, Shami, Paul J., Keefer, Larry K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622254/
https://ncbi.nlm.nih.gov/pubmed/23585982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/ForumImmunDisTher.2012006334
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