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Rapid boosting of cross-reactive memory CD8 T-cells broadens the protective capacity of the Flumist(®) vaccine

Memory CD8 T-cells recognizing conserved proteins from influenza A virus (IAV) such as nucleoprotein (NP), have the potential to provide protection in individuals who lack the proper neutralizing antibodies. Here we show that the most potent CD8 T-cell inducing influenza vaccine on the market (Flumi...

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Autors principals: Slütter, Bram, Pewe, Lecia L., Lauer, Peter, Harty, John T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622175/
https://ncbi.nlm.nih.gov/pubmed/23467935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202790
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