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P53 hinders CRISPR/Cas9 mediated targeted gene disruption in memory CD8 T cells in vivo
CRISPR/Cas9 technology has revolutionized rapid and reliable gene editing in cells. Although many cell types have been subjected to CRISPR/Cas9 mediated gene editing, there is no evidence of success in genetic alteration of antigen experienced memory CD8 T cells. In this study, we show that CRISPR/C...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541733/ https://ncbi.nlm.nih.gov/pubmed/32887747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000654 |
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