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Protective Capacity of Memory CD8(+) T Cells is Dictated by Antigen Exposure History and Nature of the Infection

Infection or vaccination confers heightened resistance to pathogen re-challenge due to quantitative and qualitative differences between naïve and primary memory T cells. Herein, we show that secondary (boosted) memory CD8(+) T cells were better than primary memory CD8(+) T cells in controlling some,...

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Detalhes bibliográficos
Main Authors: Nolz, Jeffrey C., Harty, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103642/
https://ncbi.nlm.nih.gov/pubmed/21549619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.020
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