Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly

The number of memory CD8 T cells generated by infection or vaccination correlates strongly with the degree of protection observed in infection and tumor models. Therefore, rapid induction of protective numbers of effector and memory CD8 T cells may be crucial in the case of malignancy, pandemic infe...

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Bibliographic Details
Main Authors: Pham, Nhat-Long L., Pewe, Lecia L., Fleenor, Courtney J., Langlois, Ryan A., Legge, Kevin L., Badovinac, Vladimir P., Harty, John T.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901444/
https://ncbi.nlm.nih.gov/pubmed/20616089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004661107
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