Non-nucleoside Inhibitors of BasE, An Adenylating Enzyme in the Siderophore Biosynthetic Pathway of the Opportunistic Pathogen Acinetobacter baumannii

Siderophores are small-molecule iron chelators produced by bacteria and other microorganisms for survival under iron limiting conditions, such as found in a mammalian host. Siderophore biosynthesis is essential for the virulence of many important Gram-negative pathogens including Acinetobacter bauma...

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Bibliographic Details
Main Authors: Neres, João, Engelhart, Curtis A., Drake, Eric J., Wilson, Daniel J., Fu, Peng, Boshoff, Helena I., Barry, Clifton E., Gulick, Andrew M., Aldrich, Courtney C.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621123/
https://ncbi.nlm.nih.gov/pubmed/23437866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301709s
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