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Clinical significance of P-glycoprotein immunohistochemistry and doxorubicin binding assay in patients with osteosarcoma

In 45 osteosarcoma patients, mean age 18 (4–61) years and followed for 14 (5–48) months, we studied the sensitivity to doxorubicin as well as P-glycoprotein expression, and compared these with the extent of tumour necrosis following chemotherapy. Doxorubicin assay was positive in 37 patients in whom...

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Main Authors: Kumta, S., Zhu, Q., Lee, K., Griffith, J., Chow, L., Leung, P.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620808/
https://ncbi.nlm.nih.gov/pubmed/11794258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s002640100273
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