Differential effects of mitomycin C and doxorubicin on P-glycoprotein expression.

Previous studies have demonstrated that mitomycin C (MMC) and other DNA cross-linking agents can suppress MDR1 (multidrug resistance 1) gene expression and subsequent functional P-glycoprotein (Pgp) expression, whereas doxorubicin and other anthracyclines increase MDR1 gene expression. In the presen...

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Detalhes bibliográficos
Main Authors: Maitra, R, Halpin, P A, Karlson, K H, Page, R L, Paik, D Y, Leavitt, M O, Moyer, B D, Stanton, B A, Hamilton, J W
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221775/
https://ncbi.nlm.nih.gov/pubmed/11311122
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