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P-glycoprotein Blockers Augment the Effect of Mitomycin C on Human Tenon's Fibroblasts

PURPOSE: Mitomycin C (MMC), which induces apoptosis in human Tenon's fibroblasts (HTF), is frequently used to retard wound healing after glaucoma surgery. The aim of this in vitro study was to examine whether adjunctive Verapamil and Cyclosporine could augment the cytotoxic effect of MMC on HTF...

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Detalhes bibliográficos
Main Authors: White, Andrew J. R., Kelly, Elizabeth, Healey, Paul R., Crowston, Jonathan G., Mitchell, Paul, Zoellner, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763899/
https://ncbi.nlm.nih.gov/pubmed/24049721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.2.5.1
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