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Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

PURPOSE: We investigate the effect of angiotensin receptor blockade on the migration of human Tenon fibroblasts (HTF), using irbesartan, an angiotensin II receptor type 1 (AT1R) blocker (ARB) as a potential antifibrotic agent in glaucoma filtration surgery. METHODS: Confluent HTF cultures were scrat...

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Detalhes bibliográficos
Publicado no:Transl Vis Sci Technol
Main Authors: Kim, Duri, Pattamatta, Ushasree, Kelly, Elizabeth, Healey, Paul R., Carnt, Nicole, Zoellner, Hans, White, Andrew J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896341/
https://ncbi.nlm.nih.gov/pubmed/29657902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.7.2.20
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