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P-glycoprotein Blockers Augment the Effect of Mitomycin C on Human Tenon's Fibroblasts

PURPOSE: Mitomycin C (MMC), which induces apoptosis in human Tenon's fibroblasts (HTF), is frequently used to retard wound healing after glaucoma surgery. The aim of this in vitro study was to examine whether adjunctive Verapamil and Cyclosporine could augment the cytotoxic effect of MMC on HTF...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: White, Andrew J. R., Kelly, Elizabeth, Healey, Paul R., Crowston, Jonathan G., Mitchell, Paul, Zoellner, Hans
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763899/
https://ncbi.nlm.nih.gov/pubmed/24049721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.2.5.1
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