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The co-expression of p53 protein and P-glycoprotein is correlated to a poor prognosis in osteosarcoma
Multidrug resistance (MDR), mediated by P-glycoprotein (P-gp), is an in vitro phenomenon observed within tumour cells, suggesting cross-resistance to unrelated drugs, and expression of P-gp may therefore affect the prognosis and incidence of recurrence after treatment. The mutant p53 protein causes...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619924/ https://ncbi.nlm.nih.gov/pubmed/11294418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s002640000196 |
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