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Role of SHIP1 in cancer and mucosal inflammation
The SH-2 containing inositol 5’ polyphosphatase 1 (SHIP1) is a multifunctional protein expressed predominantly, by hematopoietic cells. SHIP1 removes the 5’ phosphate from the product of PI3K, PI(3,4,5)P(3), to generate PI(3,4)P(2). Both PIP species influence the activity level of Akt, and ultimatel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620675/ https://ncbi.nlm.nih.gov/pubmed/23551094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12038 |
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