Therapeutic Potential of SH2 Domain-Containing Inositol-5′-Phosphatase 1 (SHIP1) and SHIP2 Inhibition in Cancer

Many tumors present with increased activation of the phosphatidylinositol 3-kinase (PI3K)–PtdIns(3,4,5)P(3)–protein kinase B (PKB/Akt) signaling pathway. It has long been thought that the lipid phosphatases SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) and SHIP2 act as tumor suppressors by...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fuhler, Gwenny M, Brooks, Robert, Toms, Bonnie, Iyer, Sonia, Gengo, Elizabeth A, Park, Mi-Young, Gumbleton, Matthew, Viernes, Dennis R, Chisholm, John D, Kerr, William G
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269644/
https://ncbi.nlm.nih.gov/pubmed/22033675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00178
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados